Max Planck Institute for Molecular Genetics - Ihnestraße 63-73 - 14195 Berlin - Germany - Phone: (+49 30) 8413 1150 - Fax: (+49 30) 8413 1394

Projekt "Workflows zur Analyse von Multidomän-Proteinen"

Termine

Kick-off, 8. März, 11 Uhr

Code Reviews, montags, 11 Uhr

Literatur

• Doolittle, R. F. The multiplicity of domains in proteins. Annu Rev Biochem 64, 287-314 (1995).
• Moore, A. D. et al. Arrangements in the modular evolution of proteins. Trends Biochem Sci. 33(9):444-51. (2008) - Paula
• Basu, M. K. K., Carmel, L., Rogozin, I. B. & Koonin, E. V. Evolution of protein domain promiscuity in eukaryotes. Genome research 18, 449-461 (2008). - Christoph
• Behzadi, B. & Vingron, M. Reconstructing domain compositions of ancestral multi-domain proteins. In RECOMB 2006 International Workshop, RCG 2006, 1-10 (Springer, 2006). - Franziska

Resourcen

• PFAM (domain data base) - Jan
• SMART (domain data base) - Jan
• HMMer - Maik
• Muscle - Federico
• MAFFT - Federico
• PhyML - Tobias

Entwicklung

• Ein empfohlenes Python-Tutorial
(English, short)
• Galileo Openbook on Python (Deutsch, ausführlich)
• BioPython
• Subversion - Zur Versionierung

Betreuer

• Dr. Roland Krause
  (krause@molgen.mpg.de)