Online Lectures on Bioinformatics
Here is a picture of the protein Hexokinase.
- What does Hexokinase do?
(hint: use Swissprot, Genecards, KEGG)
- Obtain the sequences of all yeast hexokinase proteins.
(hint: use Swissprot at expasy)
- Obtain the yeast hexokinase A gene.
(hint: EMBL entry SCHKA , ACcession number X03482 from EBI)
- Translate the gene and compare the protein sequence to the swissprot sequences.
(hint: use ORF Finder at NCBI)
- Obtain the genomic DNA of a human hexokinase (AC MMHEXII3 from EBI) and translate it into protein.
What's the result and why?
Compare to human protein hexokinase 2.
(hint: try ORF Finder and GENESCAN (Swissprot -> Proteomics tools...))
- Swissprot at expasy
- NCBI (ORF Finder)
- Genecards at DKFZ
Answers to the exercises.
Comments are very welcome.